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Master Thesis

Place de la photobiomodulation dans la mucite orale ?

Abstract : Introduction: Oral mucositis (OM) is a common side effect of radiotherapy (RT) or radio-chemotherapy (RT/CT) for head and neck cancers. It causes lesions leading to treatment interruptions. Publications show positive results of photobiomodulation (PBM) to treat it. Material and method: A literature search strategy was applied in Medline, selecting articles published between 2010 and 2020, to answer the following research question: "In patients treated with RT or RT/CT, what is the place of PBM in the management of OM? Results: The InGaAlP diode laser and the HeNe laser reduced OM significantly compared to placebo in 62.5% and 75% of the studies, respectively. Pain reduction was poorly documented, and when it was, it did not correlate with the reduction of analgesics. Discussion: Although PBM seems to be effective in reducing MO scores, its effectiveness on pain, painkiller consumption, compliance with treatment and the occurrence of complications remains to be defined. Conclusion: Despite its efficacy, the questions of the adjustment of the parameters of PBM and its safety on carcinologic recurrence remain to be studied.
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Master Thesis
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Submitted on : Wednesday, April 13, 2022 - 3:22:18 PM
Last modification on : Friday, April 15, 2022 - 3:30:52 AM


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  • HAL Id : dumas-03640454, version 1


Géraldine Labrosse. Place de la photobiomodulation dans la mucite orale ?. Chirurgie. 2021. ⟨dumas-03640454⟩



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