Service interruption on Monday 11 July from 12:30 to 13:00: all the sites of the CCSD (HAL, Epiciences, SciencesConf, AureHAL) will be inaccessible (network hardware connection).
Skip to Main content Skip to Navigation
Master Thesis

Artère pulmonaire et ventricule droit dans l'hypertension pulmonaire‎ : corrélation entre la TDM synchronisée à l'ECG et le cathétérisme cardiaque droit

Abstract : Purpose: To retrospectively investigate whether a relationship exists between ECG-gated-CT functional parameters (right ventricular ejection fraction (RVEF), right ventricular cardiac output (RVCO), pulmonary artery (PA) distensibility) and mean pulmonary arterial pressure (mPAP) or CO measured by right-side heart catheterization (RHC) in patients with pulmonary hypertension. Materials and Methods: This retrospective study was submitted to the institutional review board, patient consent was not required. Twenty-seven patients with PH who had undergone both ECG-gated-CT and RHC were included. Two independent observers, blinded to RHC results, measured on ECG-gated-CT: PA diameter, PA distensibility, aorta diameter, RVCO and RVEF with two methods: automatic segmentation and Simpson technique. CO and mPAP were measured on RHC. The relationship between ECG-gated-CT and RHC measurements were tested with linear regression analysis. Results: Interobserver agreement was good for all measurements (R>0.7) except for RVCO calculated with Simpson's technique (R=0.63). PA distensibility was significantly correlated to mPAP (r=-0.426, p=0.027). RVEF was correlated with mPAP only when issued from Simpson technique (r=-0.417, p=0.034). RVEF was not significantly correlated to CO, whether with segmentation or Simpson technique (p>0.2). RVCO measured with Simpson technique (r=0.487, p=0.010) and automatic segmentation (r=0.549, p=0.005) correlated equally with CO measured with RHC. Conclusion: RVEF and RVCO measured on ECG-gated-CT are significantly correlated respectively to mPAP and CO measured on RHC and could be useful for staging and follow up of patient with PH.
Document type :
Master Thesis
Complete list of metadata

Cited literature [99 references]  Display  Hide  Download

https://dumas.ccsd.cnrs.fr/dumas-00626806
Contributor : Jean-Hugues Morneau Connect in order to contact the contributor
Submitted on : Thursday, May 17, 2012 - 4:40:42 PM
Last modification on : Tuesday, May 11, 2021 - 11:36:16 AM
Long-term archiving on: : Wednesday, December 28, 2011 - 2:21:36 AM

Identifiers

  • HAL Id : dumas-00626806, version 1
  • PPN : 155153463

Citation

Élodie Abel. Artère pulmonaire et ventricule droit dans l'hypertension pulmonaire‎ : corrélation entre la TDM synchronisée à l'ECG et le cathétérisme cardiaque droit. Médecine humaine et pathologie. 2011. ⟨dumas-00626806⟩

Share

Metrics

Record views

141

Files downloads

1205