Skip to Main content Skip to Navigation
Master Thesis

Évolution clinico-biologique de 73 femmes diagnostiquées infectées par le VIH pendant la grossesse et traitées par trithérapie antirétrovirale‎ : étude au Congo-Brazzaville

Abstract : The HIV pandemic is a main public health concern in sub-Saharan Africa. The Prevention of Mother to Child Transmission programs aim to treat pregnant women with AntiRetroviral Treatment, in order to avoid the vertical virus transmission. Few data are available about the clinical and biological follow-up after delivery. This retrospective and descriptive study was conducted in the day care centre run by the French Red Cross in Pointe-Noire, Republic of Congo. Seventy-three patients were included. They were given either a prophylactic treatment which was stopped after delivery or breastfeeding (30 patients), or a long-term treatment for their own health (43 patients). The education level was low; most of them were housewives or housecleaners (44%), or had a street seller activity (27,4%). The clinical follow-up was good as 100% of patients went to their consultation on M24, 84% on M30 and 81% on M36. The biological follow-up based on CD4 and Viral Load measure was rarely performed, due to the supply chain failures of biologic reactive, and despite the good technic and human support available. Three deaths occurred during the 36 months of follow-up. The clinical evolution of patients who stopped the ARV seems to be as safe as evolution of women who kept on with treatment. No patient treated with prophylactic ARV went through adverse effect, compared to 6 women in the life-time treatment group. In order to improve the guidelines, we need to take into account, further than the biomedical part, the economic, social and cultural aspects of sub-Saharan African context.
Document type :
Master Thesis
Complete list of metadata

Cited literature [32 references]  Display  Hide  Download

https://dumas.ccsd.cnrs.fr/dumas-00911018
Contributor : Jean-Hugues Morneau <>
Submitted on : Thursday, November 28, 2013 - 3:56:32 PM
Last modification on : Tuesday, May 11, 2021 - 11:36:16 AM
Long-term archiving on: : Monday, March 3, 2014 - 6:16:41 PM

Identifiers

  • HAL Id : dumas-00911018, version 1

Citation

Hélène Bruet-Mochet. Évolution clinico-biologique de 73 femmes diagnostiquées infectées par le VIH pendant la grossesse et traitées par trithérapie antirétrovirale‎ : étude au Congo-Brazzaville. Médecine humaine et pathologie. 2013. ⟨dumas-00911018⟩

Share

Metrics

Record views

179

Files downloads

808