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Master Thesis

Gender differences in early versus late intensive care unit admission for community-acquired pneumonia patients

Abstract : Objectives: The objective was to compare the early and late admission to intensive care unit (ICU) for male and female patients hospitalized with community-acquired pneumonia (CAP). Methods: We performed a Post hoc analysis of the original data from the Emergency Department Community-Acquired Pneumonia and Pneumocom-1 prospective multicenter cohort studies of adult patients hospitalized with CAP. The primary endpoint was the ICU admission and timing: early (i.e., ICU admission on the day of emergency department presentation), late, and no ICU admission. The secondary endpoint was the 28-day mortality. Results: 1,368 (53.5%) male patients and 1,190 (46.5%) female patients were included in the sample analytical. Male patients were more severe than female patients (assigned to Pneumonia Severity Index classes IV-V; 53.6% vs. 37.3%) and had higher rates of early ICU admission (8.3% vs. 7.1%) and late ICU admission (6.7% vs. 4.5%). Men with severe CAP (Pneumonia Severity Index class V) had a lower rate of early ICU admission (17% vs. 26%), which was compensated by a higher percentage of late ICU admission (10% vs. 2%), compared to women (p for interaction = 0.02). Comparable 28-day mortality rates were observed for male and female patients, even after adjustment for severity and ICU admission timing. Conclusions: This study suggests that male patients with severe CAP who require early ICU admission are less identified than female patients. For the first time, a gender bias is highlighted in the process of care of CAP patients in favor of women.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-01072381
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Submitted on : Wednesday, October 8, 2014 - 9:57:24 AM
Last modification on : Tuesday, May 11, 2021 - 11:36:17 AM
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  • HAL Id : dumas-01072381, version 1

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Bastien Boussat. Gender differences in early versus late intensive care unit admission for community-acquired pneumonia patients. Human health and pathology. 2014. ⟨dumas-01072381⟩

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