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Master Thesis

Évaluation des apports nutritionnels chez des nouveau-nés prématurés au CHU de Bordeaux : étude observationnelle en 2014

Abstract : Introduction: Preterm nutrition remains a challenge. Several studies have shown the difficulties to achieve and maintain the recommended intakes. Aim: After the optimization of the local nutrition policy, we propose to assess the nutritional intakes really received by preterm infants by comparing with the literature’s recommendations. Methods: This is a single-center prospective observational study conducted between 01/02/14 and 31/08/14 in all infants born less than 33 weeks of amenorrheas hospitalized in the Bordeaux University Hospital neonatal intensive care and neonatology for a minimum of 6 weeks. Anthropometric monitoring and collection of nutritional and general data was conducted until hospital discharge. For each child, we calculated the weekly weight z score. Nutrient intakes were compared with current recommendations (ESPGHAN 2005 and 2010, Nutritional care of preterm infants) Results: 41 children were included with a median gestational age of 29 [28 ; 30] weeks of amenorrheas and a median birth weight of 1146 [900; 1340] grams. The recommended energy intakes are achieved after three day of life. After 6 weeks, the cumulative energy deficits are -28.0 [-302.7; 400.9] kcal/kg. The recommended protein intake are achieved from the 4th day of life and become insufficient from the third week of life which causes a cumulative protein deficit reaching of -7.5 [-13.7; -0.68] kcal/kg at 6 weeks of age. We observe at the same time a fall in z-score variations from the third week of life to reach -0.7 [-0.4; -0.8] at 6 weeks of life. Conclusion: Energy, carbohydrate and fat intakes are consistent with current recommendations. However, this optimized protocol does not allow a sufficient protein intake from the third week of life. In our study, newborns are underweight growth restriction that could be linked to the magnitude of protein deficits.
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Master Thesis
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Submitted on : Friday, July 17, 2015 - 3:09:23 PM
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Anne-Sophie Pagès. Évaluation des apports nutritionnels chez des nouveau-nés prématurés au CHU de Bordeaux : étude observationnelle en 2014. Médecine humaine et pathologie. 2015. ⟨dumas-01178158⟩



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