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Master Thesis

La maladie de Kawasaki de l'enfant, île de la Réunion, étude rétrospective multicentrique de 2008 à 2014

Abstract : Kawasaki disease in infants on Reunion Island: a retrospective multicenter study looking back at 105 cases from 2008 to 2014. Objectives: To estimate the incidence of Kawasaki disease in infants on Reunion Island. To observe the eventual epidemiological, clinical or pathogenic characteristics by taking into account the unique multi ethnic population and geographical location of the Reunion Island. Method: A retrospective multicenter study of four pediatric hospital units within the department, and the observation of 105 Kawasaki disease cases from 2008 to 2014. Results: The average occurrence of Kawasaki disease in infants was 20,8 for every 1000 under the age of 5. That is 2 to 4 times higher than in mainland France. This cohort was relatively young, aging between 6 months and 5 years old (80%). Seasonality was also noticeable. The clinic was susceptible to a large proportion of incomplete forms. With 14 dilatations and aneurysm of the coronary arteries (13.1%), the cardiac complications were significant during the acute stage. The risk factors of aneurysm development in children seemed to be under 1 year of age and the importance of the inflammatory syndrome. The average timeline for the 1st immunoglobulin injection was 7.5 days. Conclusion: The high incidence of Kawasaki disease on Reunion Island, which is marked by a large proportion of incomplete forms, calls for a higher vigilance by health professionals on Reunion Island in order to reduce eventual cardiac complications.
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https://dumas.ccsd.cnrs.fr/dumas-01253428
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Submitted on : Sunday, January 10, 2016 - 2:26:03 PM
Last modification on : Wednesday, August 23, 2017 - 4:31:17 PM
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Thomas Garrain. La maladie de Kawasaki de l'enfant, île de la Réunion, étude rétrospective multicentrique de 2008 à 2014. Médecine humaine et pathologie. 2015. ⟨dumas-01253428⟩

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