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Master Thesis

Épilepsie du sujet âgé : évaluation prospective d'un outil d'aide au diagnostic des crises épileptiques

Abstract : Seizures are frequent in the elderly, but their diagnosis can be arduous. The objective of this work was to validate an algorithm for the diagnosis of seizures in elderly people by a prospective study. The algorithm was developed beforehand by multidisciplinary group of neurologists and geriatricians and was validated by a multicenter retrospective analysis. In our study, this algorithm has been translated into score to simplify its use. The score was tested prospectively in 2 emergency department in France for 15 months. It was applied to all patients. The score included 7 items (6 clinical items, 1 electroencephalographic item), each associated with a score. 90 elderly patients were included, in Bordeaux’s Hospital, and in Arcachon’s hospital. Patients were referred for a confusion (47%), a fall (21%), a faintness (20%), unconsciousness (14%), a transient focal deficit (4%). The diagnosis provided by the algorithm was compared to the clinical diagnosis of the experts. The score ≥ 4 was the most relevant. The sensitivity of the test was 93% and the specificity was 85%. A score ≥ 4 points suggest an epileptic seizure. A score < 4 points, eliminated the diagnosis. In conclusion, this study validated the use of the diagnostic algorithm to help diagnosis epileptic seizures in the elderly.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-01316778
Contributor : Bu Carreire Université de Bordeaux <>
Submitted on : Tuesday, May 17, 2016 - 4:34:04 PM
Last modification on : Wednesday, August 23, 2017 - 4:33:34 PM
Long-term archiving on: : Friday, August 19, 2016 - 4:50:54 PM

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Agathe Alberti. Épilepsie du sujet âgé : évaluation prospective d'un outil d'aide au diagnostic des crises épileptiques. Médecine humaine et pathologie. 2016. ⟨dumas-01316778⟩

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