Skip to Main content Skip to Navigation
Master Thesis

Évaluation de l’oxygénation cérébrale par spectroscopie du proche infra-rouge (NIRS) dans la chirurgie carotidienne au CHU de Bordeaux

Abstract : Objective: show that the monitoring of cerebral oxygenation (RsO2) via near-infrared spectroscopy (NIRS) can reduce ischemic cerebral lesions volume in MRI. Methods: In this prospective, randomized, controlled study were included 124 patients who underwent carotid endarterectomy between April, 2012 and November, 2015. The RsO2 was recorded for all (Monitor INVOS 5100C TM, COVIDIEN ®). In the blind group, the monitor was hidden. In the NIRS group, an algorithm of treatment was used if the patient presented a reduction in rSO2 > 15% from the baseline. Every patient had an MRI before and after surgery. Primary end point was the volume of the new ischemic lesion. Results : 124 patients were included, 62 in every group. 48% presented a reduction in the rSO2 > 15% of the baseline. There was 0,4 ± 1,2 new cerebral lesion in the blind group against 0,9 ± 2,7 in the NIRS group (p=0,205). The volume of the new ischemic lesions was not significantly higher in the blind group with respectively 6,7 ± 43 ml versus 2,4 ± 12 ml with an CI in 95% [-7,185; 15,724] and p=0,462. Conclusions: Hemodynamic optimization thanks to monitoring of cerebral oxygenation does not reduce significantly the new ischemic lesions volume.
Document type :
Master Thesis
Complete list of metadatas

https://dumas.ccsd.cnrs.fr/dumas-01425684
Contributor : Bu Carreire Université de Bordeaux <>
Submitted on : Tuesday, January 3, 2017 - 5:25:57 PM
Last modification on : Wednesday, August 23, 2017 - 4:29:10 PM
Long-term archiving on: : Tuesday, April 4, 2017 - 3:06:14 PM

Identifiers

  • HAL Id : dumas-01425684, version 1

Collections

Citation

Victoria Dahlet. Évaluation de l’oxygénation cérébrale par spectroscopie du proche infra-rouge (NIRS) dans la chirurgie carotidienne au CHU de Bordeaux. Médecine humaine et pathologie. 2016. ⟨dumas-01425684⟩

Share

Metrics

Record views

136

Files downloads

569