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Master Thesis

La lymphopoïèse B chez le Danio rerio

Abstract : B lymphopoiesis is the set of biologicals processes of mature B cell (LB) formation. From embryonic hempatopoiesis to adult hematopoiesis, from antigen meeting to effectrice stage and immune memory creation, B maturation thematics are various and complicated. Mouse is actually the main support for immunologic studies, but other species show specific and unique advantages. Danio rerio or zebrafish is one of them. This vertebrate present many orthologues genes with mammals and prove his utility. Tools like Immunoglobulin repertoire analysis or target surface cell marquor like CD79 are differents ways to clarify zebrafish B cell developpment, for exemple demonstrate existence of pre-B cell stage.
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Master Thesis
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Contributor : Bu Carreire Université de Bordeaux <>
Submitted on : Wednesday, March 21, 2018 - 12:52:22 PM
Last modification on : Saturday, March 31, 2018 - 1:23:05 AM
Long-term archiving on: : Thursday, September 13, 2018 - 8:48:34 AM


  • HAL Id : dumas-01739764, version 1



Olivia Derne. La lymphopoïèse B chez le Danio rerio. Sciences pharmaceutiques. 2017. ⟨dumas-01739764⟩



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