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Master Thesis

Étude randomisée en cross-over évaluant « le syndrome du pyjama bleu » dans l’épisode dépressif majeur

Abstract : Background: This paper introduces a “blue pyjama syndrome” (i.e. wearing hospital pyjamas results in an exaggerated impression of severity), a phenomenon that has not been described in earlier literature despite the fact that pyjamas are an emblematic, and possibly stigmatizing aspect for psychiatric inpatients. Methods: A 5-day, prospective, randomized, cross-over study performed in a French mood disorder unit for inpatients. At Day 1 (D1) and Day 5 (D5) of hospitalization, two 5-minute standardised video interviews were recorded with patients in pyjamas or in day clothes (the sequence was randomly allocated). Psychiatrists unaware of the study objective assessed the videos and quote their clinical global impressions (CGI, with a score ranging from 1 to 7). A mixed model was used to estimate the differences between pyjamas and day clothes and between D1 and D5. Findings: Of 30 participants with major depressive episode selected for inclusion, 26 participants (69 % women) provided useable data for an evaluation by 10 psychiatrists. Pyjamas significantly increased the psychiatrists’ CGI ratings of disease severity by 0.65 [0.27; 1.02] points. The psychiatrists’ global impressions also rated patients as significantly less severe at D5 in comparison with D1 by -0.66 [-1.03; -0.29] points. Interpretation: The “blue pyjama syndrome” is in the same order of magnitude as the difference observed after a week of hospitalisation. More research is needed to know whether, by affecting physicians’ general perceptions of mental health, pyjamas could affect clinical decisions and diagnostic accuracy. Funding: Rennes University Hospital, France. Trial registration: Open Science Framework: osf.io/gcw9e
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https://dumas.ccsd.cnrs.fr/dumas-01755330
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Submitted on : Wednesday, June 6, 2018 - 12:19:37 PM
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Héléna Delmas. Étude randomisée en cross-over évaluant « le syndrome du pyjama bleu » dans l’épisode dépressif majeur. Sciences du Vivant [q-bio]. 2016. ⟨dumas-01755330⟩

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