Solutions et questions face à l'émergence d'une épidémie d'hépatite A à Marseille en 2017

Abstract : Since 2016, an acute hepatitis A outbreak spread in Europe in low-endemicity countries, mainly affecting men who have sex with men (MSM) who are positive or negative for the human immunodeficiency virus (HIV)[1], despite the vaccine recommendations put in place since 2003[2]. In France and more specifically in PACA region, the Regional Health Agency warned about an hepatitis A outbreak in the second trimester of 2017, in Nice, and then in Toulon with an incidence rate four times greater than in 2016[3]. The purpose of my work was first to describe this outbreak in Marseille from all the cases hospitalized at the APHM in 2017. In a second step, it was to describe the outbreak in an high risk group which was MSM-HIV followed at the IHU Mediterranean Infection (cohort of 2300 patients). Several questions then came up: Why this outbreak? Especially reaching MSM-HIV patients? How to stop it? We have tried to respond with solutions, described here as the third part of my work, which are the result of an emergency vaccination program combined with a study of sexual behaviour and knowledge about sexually transmitted infections (STIs).
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Submitted on : Friday, December 14, 2018 - 9:46:34 AM
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Aurélie Martin. Solutions et questions face à l'émergence d'une épidémie d'hépatite A à Marseille en 2017. Sciences du Vivant [q-bio]. 2018. ⟨dumas-01954959⟩



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