Skip to Main content Skip to Navigation
Master Thesis

Facteurs pronostiques maternels de complications obstétricales des grossesses obtenues par FIV : mise au point d’un outil de dépistage par nomogramme

Abstract : Introduction: In a previous study, we showed that the obstetric complications rate after IVF pregnancy was 40 %. The main objective of our study was to determine prognosis maternal factors which influence the IVF pregnancy outcome. Methods: We conducted a non experimental retrospective monocentric study. We collected all IVF pregnancies more than 22 SA obtained in our reproductive medicine unit between January 1st, 2012 and December 31st, 2015. We studied all the maternal characteristics and their pregnancy outcome. Results: we included 498 IVF pregnancies. The most significant prognosis maternal factors for obstetric complications were the maternal age upper to 40 years (3.0 [95 % IC 1.30-7.09] P = 0.10), the daily maternal smoking upper to 10 cigarettes (7.1 [95 % IC 1.22-41,74] P =0.029), the maternal obesity (2.2 [95 % IC 1.19-4,07] P = 0.012), the endometriosis stage III and IV (6.4 [95 % IC 1.52-27,04] P = 0.011 and a history of ovarian hyperstimulation syndrome in early pregnancy (5.7 [95 % IC 1.29-24.74] P = 0.021). Increase of the risks was independent of the pregnancy type (singleton or twin) and allowed the elaboration of 2 nomograms. Conclusion: We highlighted a link between some maternal factors and the increase of obstetric complications after IVF. The screening of these factors during a personalized pre-conceptional consultation is major to identify the high-risk pregnancies and adapt their monitoring.
Complete list of metadatas

Cited literature [13 references]  Display  Hide  Download

https://dumas.ccsd.cnrs.fr/dumas-01957690
Contributor : École Universitaire de Maïeutique Marseille Méditerranée (eu3m) <>
Submitted on : Monday, December 17, 2018 - 3:03:18 PM
Last modification on : Monday, July 6, 2020 - 4:04:37 PM
Long-term archiving on: : Monday, March 18, 2019 - 3:58:37 PM

File

PORTAL_PRONOSTICS_MATERNELS_CO...
Files produced by the author(s)

Identifiers

  • HAL Id : dumas-01957690, version 1

Citation

Alice Portal. Facteurs pronostiques maternels de complications obstétricales des grossesses obtenues par FIV : mise au point d’un outil de dépistage par nomogramme. Gynécologie et obstétrique. 2018. ⟨dumas-01957690⟩

Share

Metrics

Record views

132

Files downloads

512