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Master Thesis

Proposition d’un programme de promotion de la vaccination contre les papillomavirus en Isère 2018 - 2022

Abstract : Introduction. The administration of Isère decided to launch an immunization campaign against Human Papillomavirus (HPV) from 2018 to 2022. In France, in 2017, HPV uptake was about 21%. In Isère, it is even lower (18%). However, this vaccine can prevent more than 90% of the cancers and lesions associated with HPV (6,000 cancers/ year in France). We aim to build a program that doubles the vaccination coverage against HPV by 2022. Method. We performed a literature realist review on three points. We first identified candidate theories that explain changes in health behavior and developed a theoretical framework. Then, this framework guided our selection, appraisal of studies. Indeed, we reviewed interventions according to their potential effect on immunization change to ultimately increase HPV immunization coverage. Finally, through a review of documents, we deepened our knowledge on the context in Isère. Results. We identified three theories; their combinations include intention and planning of action as determinants of changes. Otherwise we selected 58 primary studies and 8 systematic reviews evaluating vaccination uptake. The most efficient strategies are environmental and school-based. They induce a change in norms and help get over the intention to the action. On these results and given the context in Isère, we suggest a promotional program in Isère. It is a multi-components program directed at girls, their parents as well as physicians, generalists and specialists. Conclusion. Base on theoretical insights, using evidence and reviewing local document, we developed a proposal for a HPV immunization campaign in Isère. This proposal will provide useful information for local program implementers and policy makers. It will also serve the conception of the program evaluation.
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Master Thesis
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Submitted on : Friday, May 3, 2019 - 11:34:33 AM
Last modification on : Tuesday, May 11, 2021 - 11:36:24 AM


  • HAL Id : dumas-02118676, version 1


Lucie Pothrat. Proposition d’un programme de promotion de la vaccination contre les papillomavirus en Isère 2018 - 2022. Médecine humaine et pathologie. 2019. ⟨dumas-02118676⟩



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