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Master Thesis

Intérêt du CPP-ACP dans la reminéralisation des lésions d'usures érosives : une revue systématique

Abstract : Erosion is the most frequent type of usury within children and teenagers. Dentists and surgeons are concerned with the screening, risk-assessment and prevention of this pathology. Dental erosion is defined by a loss of a superficial solid dental substance caused by a chemical process, without bacterial involvement. To fight against this demineralization, there exist remineralizing agents such as: fluor (the most commonly used at this time) and casein phosphopeptide combined with amorphous calcium phosphate (CPP-ACP). They allow a remineralization of the surface of tooth enamel as well as an inhibition of the demineralization and salivary pH stabilisation around physiological values. Number of studies have shown the interest of CPP-ACP in the remineralization of beginning carious lesions, but at this time, no existing systematic literature review has identified the articles dealing with CPP-ACP and erosive wear injuries. Our work, through a systematic literature review, aimed to evaluate the efficiency of CPP-ACP only and of fluorine + CPP-ACP on erosive wear injuries. After screening three databases: Pubmed, Cochrane and Scopus, and, following the PRISMA criteria, 44 publications were selected. In total, there are 24 studies where CPP-ACP has a positive effect on erosion, 3 studies show that CPP-ACP has a more effect than fluorine, and 5 studies demonstrate that the combination CPP-ACP + F has a greater effect than CPP-ACP on its own. Only 7 studies show that CPP-ACP would not have any beneficial effect on the remineralization of erosive wear injuries and 5 studies point that CPP-ACP + F does not present positive effect on erosion. There is indeed a beneficial CPP-ACP on erosive wear injuries.
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https://dumas.ccsd.cnrs.fr/dumas-02292081
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Submitted on : Thursday, September 19, 2019 - 1:57:04 PM
Last modification on : Sunday, September 22, 2019 - 1:12:11 AM
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Blandine Daubricourt. Intérêt du CPP-ACP dans la reminéralisation des lésions d'usures érosives : une revue systématique. Sciences du Vivant [q-bio]. 2019. ⟨dumas-02292081⟩

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