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Master Thesis

Revue de la littérature sur la transformation maligne du lichen plan buccal

Abstract : Oral Lichen Planus (OLP) is an inflammatory and chronic mucocutaneous disease. It can affect all the mucosal membranes of the mouth. The etiology of this disorder is still unknown. It concerns a population aged forty-sixty, mostly women. The malignant transformation of OLP has been known since Hallopeau, in 1910. Because of it, the World Health Organization has classified OLP among the oral potentially malignant disorders. In the scientific literature, many studies have focused on the characteristics and clinical manifestations of OLP and its rate of malignant transformation that is still debated. The objective of this work is, through a review of the literature, to highlight the frequency of malignant transformation of OLP, including the clinical characteristics of the populations studied. The analysis of studies selected by our research over the last ten years provides some answers on the role of cellular biomarkers involved in the malignant transformation of OLP and their interest in its early detection. This work ends with an illustrated and commented presentation of clinical cases of malignant transformation of OLP.
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Master Thesis
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Submitted on : Tuesday, September 24, 2019 - 3:36:06 PM
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  • HAL Id : dumas-02295906, version 1


Livia Roux. Revue de la littérature sur la transformation maligne du lichen plan buccal. Chirurgie. 2019. ⟨dumas-02295906⟩