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Master Thesis

Sommeil des patients atteints de BPCO et son impact sur les exacerbations sévères

Abstract : Introduction: Patients with COPD have poor sleep quality and present significant physiological adaptation such as the activation of the sternocleidomastoid (SCM). Objective: To describe the sleep of patients with COPD and evaluate the impact of SCM activation. Results: From October 2015 to December 2016, 29 COPD patients underwent a full polysomnography. 3 showed no SCM activation, 17 occasional SCM activation and 9 permanent SCM activation. Patients with permanent SCM activation have less total sleep time compared to the occasional SCM activation group (289 [192-354] vs 386 [320-420] min., P = 0.010), less paradoxical sleep (SP) (11% [0-17] vs 24% [16-28], p = 0.002) and their sleep efficiency was lower (52% [36-62] against 74% [64-80], p = 0.02). Exacerbation-free survival is shorter in these group (permanent SCM activation), regardless of the number of previous exacerbations or FEV1. Conclusion: Sleep of patients with COPD is strongly disturbed with non physiological adaptation such as the activation of SCM during REM sleep. This activation is associated with a risk of severe exacerbation within 6 months.
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https://dumas.ccsd.cnrs.fr/dumas-02384894
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Submitted on : Thursday, November 28, 2019 - 3:34:25 PM
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  • HAL Id : dumas-02384894, version 1

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Léo Grassion. Sommeil des patients atteints de BPCO et son impact sur les exacerbations sévères. Sciences du Vivant [q-bio]. 2018. ⟨dumas-02384894⟩

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