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Master Thesis

Outils d’amélioration de la mise en oeuvre d’une étude de recherche clinique multicentrique. L’exemple du projet DREPADO

Abstract : In the field of clinical research, the implementation of a multicenter study presents several complex aspects including the geographical distance of the centers, the large number of collaborators needed and the complexity of the subject of study. The proposed work is a report of a Master 1 internship in Public Health, carried out as part of a clinical research study: "DREPADO - Impact of a pediatric-adult transition program on the health status of adolescents with sickle cell disease". This national multicenter randomized controlled clinical trial, coordinated by the Hospices Civils de Lyon, is currently underway in Lyon. It must open officially in the other participating centers from September 2019. Given the complexity of DREPADO, the objective of this internship was to propose to the coordination team the relevant tools to improve its multicentric implementation. To meet this objective, the proposed work is based on two distinct but complementary missions, which were both based on the needs of the coordination team, on the recommendations of the literature, and on the situation report on the existing practices and tools. The first mission is to improve the evaluation of the implementation of the project transition program, and proposes the creation of a questionnaire. The second mission aims at improving communication in the implementation of DREPADO, and proposes the implementation of two communication tools: a monthly newsletter and an information brochure. These tools will improve the implementation of the DREPADO clinical research study.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-02446316
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Submitted on : Monday, January 20, 2020 - 5:31:26 PM
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Pauline Gallean. Outils d’amélioration de la mise en oeuvre d’une étude de recherche clinique multicentrique. L’exemple du projet DREPADO. Santé publique et épidémiologie. 2020. ⟨dumas-02446316⟩

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