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Master Thesis

Rôle du microbiote intestinal sur le risque palustre et mise en perspective de thérapies antipaludiques innovantes

Abstract : Malaria remains one of the most deadly infectious diseases in the world and has been experiencing a worrying upsurge in recent years, mainly attributed to the spread of resistance from Anopheles mosquitoes to insecticides and from plasmodium to drugs. Studies of the interactions of mammals (human and mice) gut microbiota with plasmodium put in evidence a protective effect of certain gut bacteria, on the one hand against the susceptibility to infection by malaria and on the other hand against the risk of developing severe malaria. These results encourage the search for innovative vaccines and probiotics for prophylaxis in the pursuit of the fight against malaria.
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Master Thesis
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Amélie Roussel-Dupre. Rôle du microbiote intestinal sur le risque palustre et mise en perspective de thérapies antipaludiques innovantes. Sciences du Vivant [q-bio]. 2019. ⟨dumas-02465322⟩

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