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Master Thesis

Pronostic des infarctus cérébraux traités par recanalisation (thrombolyse et/ou thrombectomie) entre 2013 et 2017 en Normandie Occidentale‎

Abstract : Introduction. Socio-economic factors involvement in response to the reperfusion treatment of acute ischemic stroke is badly known. The aim of the study is to evaluate functional outcome at 3 months of ischemic stroke treated by reperfusion and to evaluate if this prognosis relies on socio-economic factors. Methods. This retrospective observational study include all patients living in West Normandy who benefits intraveinous thrombolysis and/or mechanical thrombectomy treatment between 2013 and 2017. Datas was collected in the 5 regional stroke units. Socio-economic informations of the city of residence was collected and a socio-economic deprivation index calculated. Modified Rankin scale ≤ 2 define a good functional outcome. Results. There was 893 reperfusion treatment with good functional outcome at 3 months in 363 (49%) cases. Multivariate analysis ajusted on age and on initial NIHSS found that no ischemic cardiopathy (OR=0,63, IC 95% [0,40 ; 0,99]) and ischemic stroke (OR=0,48, IC 95% [0,25 ; 0,92]) history was associated with good outcome. On univariate analysis, a good socioeconomic deprivation index was associated with good outcome (p=0,023). Significance vanished in multivariate analysis. Discussion. Our findings on patient outcome at 3 months are agreed with those rapported in literature and international registers. No evidence of socio-economics factors impact on outcome has been demonstrated.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-02473370
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Mathieu Croisille. Pronostic des infarctus cérébraux traités par recanalisation (thrombolyse et/ou thrombectomie) entre 2013 et 2017 en Normandie Occidentale‎. Médecine humaine et pathologie. 2019. ⟨dumas-02473370⟩

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