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Master Thesis

Intérêt des probiotiques dans la prise en charge des pathologies parodontales et carieuse : revue systématique depuis 2015

Abstract : Prevention and gold-standard treatment of oral diseases are dealing with some limitations, especially long-term sustainability of outcomes or deep periodontal pockets. International Dental Research hopes to improve them by designing new therapies, such as probiotics medications. Through our review, we try to determine if probiotics would provide opportunities for prevention and treatment of oral diseases. 12 clinical studies of the first part explore the value of using probiotics in the medical care of periodontal diseases. The second part, including 12 studies, evaluate the interest of probiotics administration in order to improve tooth decay prevention. Although some studies report clinical, microbiological or immunological improvements, it is difficult to conclude that there is a real interest of probiotics in prevention or treatment of periodontitis and tooth decay. Main reasons are mixed results and important heterogeneity of the studies, inducing a significant risk of bias. To conclude further longer-term studies with more patients are required in order to better understand the interactions between probiotics and oral health.
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https://dumas.ccsd.cnrs.fr/dumas-02496239
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Nicolas Horion. Intérêt des probiotiques dans la prise en charge des pathologies parodontales et carieuse : revue systématique depuis 2015. Sciences du Vivant [q-bio]. 2020. ⟨dumas-02496239⟩

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