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Master Thesis

Intérêt de la biométrie et de la mesure de la position du cristallin par OCT swept-source dans l'estimation de la position des implants intraoculaires après chirurgie de la cataracte

Abstract : Objectives: the aim of this study was to develop and evaluate the accuracy of a novel formula integrating data on anatomy and position of the crystalline lens based on swept-source OCT (SS-OCT) to predict the postoperative ELP in cataract surgery compared with the currently used formulas. Methods: crystalline lens biometric parameters were assessed in vivo by a SS-OCT (CASIA2, Tomey, Japon) under mydriatic conditions in a single centre prospective study. Axial length (AL) and White-to-white were measured with an optical biometer (IOLMaster 500). Effective lens position (ELP) was measured with the CASIA2 device 1-month after surgery. Data were randomly divided into two groups. The first group (N = 31 eyes) led us to develop a new formula integrating anterior chamber depth (ACD), depth to lens equator (DELP) and lens thickness (LT) thanks to multiple linear regression analysis. The new formula was tested in the second group (N = 30 eyes). R2 of the new formula was compared to the R2 of the SRK/T and Haigis formulas. Results: sixty-one eyes of 41 patients were included. Mean age was 71,9 +/- 7,4 years (51-89). Mean AL, ACD, keratometry and LT were 23,8 +/- 1,2 mm, 2,60 +/- 0,38 mm, 43,9 +/- 1,6 D et 4,59 +/- 0,43 mm respectively. Depth to lens equator plane was more correlated to ELP than ACD: R=0,79; R=0,63; p<0,001. R2 of the new formula was superior to R2 of the SRK/T and Haigis formulas: R2 = 0,70 versus R2 = 0,11 (SRK/T), R2 = 0,17 (Haigis). Effective lens position estimated by the new formula (4,96 +/- 0,21) was not significantly different from ELP measured with SS-OCT (5,06 +/- 0,32) whereas ELP predicted by SRK/T and Haigis was significantly superior to the measured ELP (SRK/T 5,92 +/- 0,45; Haigis: 5,37 +/- 0,34). Mean absolute prediction error of the ELP was significantly inferior for the new formula compared to the SRK/T and Haigis formulas. Conclusion: the new formula incorporating data on anatomy and position of the crystalline lens measured by OCT swept-source predicts more accurately the postoperative ELP than the commonly used formulas.
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  • HAL Id : dumas-02497475, version 1

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Rabia Bentata. Intérêt de la biométrie et de la mesure de la position du cristallin par OCT swept-source dans l'estimation de la position des implants intraoculaires après chirurgie de la cataracte. Sciences du Vivant [q-bio]. 2019. ⟨dumas-02497475⟩

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