Skip to Main content Skip to Navigation
Master Thesis

Influence du besoin d’uriner sur la sensibilité rectale chez des patients avec sclérose en plaques et troubles ano-rectaux

Abstract : Aims: the primary aim of this study was to assess the effect of strong desire to void (SDV) on rectal sensory function in patients with multiple sclerosis (PwMS) and anorectal disorders (ARD). The secondary aim was to identify clinical, urodynamic or manometric factors associated with greater rectal sensory function impairment at SDV in this population. Methods: thirty PwMS (mean age 49 ± 10.9 years) with anorectal disorders participated in this observational study. Rectal sensory function during anorectal manometry was recorded at strong desire to void and after urination (PV, post void). Primary outcome was the desire to defecate volume. Secondary outcomes were first perception and maximum tolerated threshold volumes, presence and modulation of recto-anal inhibitory reflex (RAIR). Results: the mean desire to defecate volume was 125 ± 59 mL at SDV and 104 ± 64 mL at PV (p<0.001). The mean maximum tolerated volume was 167 ± 61 mL at SDV versus 141 ± 64 mL after urination (p = 0.01). The other parameters were not different between SVD and PV conditions. No predictive factors for greater impairment of rectal sensory function at SDV were identified. Conclusion: this study suggests a clinical impact of bladder sensation and thus bladder capacity on rectal sensory function in PwMS and anorectal disorders, assessed by a lower threshold of desire to defecate volume after urination compared with SDV.
Complete list of metadata

Cited literature [84 references]  Display  Hide  Download
Contributor : Médecine Ub Connect in order to contact the contributor
Submitted on : Wednesday, March 4, 2020 - 11:23:20 AM
Last modification on : Wednesday, March 18, 2020 - 1:18:18 AM
Long-term archiving on: : Friday, June 5, 2020 - 1:00:43 PM


 Restricted access
To satisfy the distribution rights of the publisher, the document is embargoed until : 2021-11-14

Please log in to resquest access to the document


  • HAL Id : dumas-02498188, version 1



Camille Pouyau. Influence du besoin d’uriner sur la sensibilité rectale chez des patients avec sclérose en plaques et troubles ano-rectaux. Sciences du Vivant [q-bio]. 2019. ⟨dumas-02498188⟩



Record views