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Master Thesis

Trouble du comportement alimentaire et diabète : caractéristiques cliniques et anthropométriques

Abstract : Introduction: Eating disorders (ED) are more common in subjects with diabetes than in general population. There are associated with decreased life expectancy and earlier diabetes complications. The phase angle measured by Bioelectrical impedance analysis (BIA) reflects body composition and is a predictive marker of mortality in many diseases. The objective of this study was to compare phase angle values in patients with ED associated with diabetes (cases) or without (controls). Method: A retrospective analysis of 187 patients followed at the Grenoble ED Center between March 27, 2018, and December 30, 2020, was performed. Clinical and anthropometric data obtained with BIA were collected. Nine diabetic cases with ED were identified in our cohort. Results: Diabetic patients with ED represent a heterogeneous population with multiple factors involved in the occurrence of ED. A propensity score matches 9 cases with 25 controls from the cohort according to age, sex, type of ED, BMI, to obtain two comparable groups. The median phase angle values is 5.28 ¬[4,93-5,78] in controls and 6.13 [5,26-6,25] in cases. There was no statistically significant differences in phase angle or other body composition parameters between the two groups. Conclusion: Evidence from literature supports changes in body composition and more severe prognoses for ED patients with diabetes than without. We did not find any decrease in phase angle values in patients with ED and diabetes. However, the small number of cases as well as the high clinical heterogeneity of these patients limited our results interpretation.
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Master Thesis
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Submitted on : Friday, October 2, 2020 - 4:43:47 PM
Last modification on : Friday, November 27, 2020 - 3:56:52 PM
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  • HAL Id : dumas-02956383, version 1

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Sarah Chalopin. Trouble du comportement alimentaire et diabète : caractéristiques cliniques et anthropométriques. Médecine humaine et pathologie. 2020. ⟨dumas-02956383⟩

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