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Master Thesis

Analyse rétrospective sur trois ans des Interventions Pharmaceutiques au Centre Hospitalier Universitaire de Toulouse

Abstract : Clinical pharmacy has a major role to secure drug circuit and to prevent iatrogen events. Pharmaceutical analysis can generate pharmaceutical interventions (PI) for prescribers, in order to optimize prescribtions. At the Toulouse University Hospital, between 2016 and 2019, 59,325 IPs were performed in the prescription assistance software. Analysis of these PIs shows that : - most frequent PIs concern inappropriate dosages (more than 25%), untreated indications (14.1%), non-compliances with guidelines (14.1%), inappropriate routes or administrations (11, 2%), and errors related to computerization (9%) ; - 50% of the PIs relate to 35 molecules, mainly drugs for nervous system, blood, digestive/metabolic and cardiovascular systems. A detailed analysis of these PIs is presented. These results are broadly similar to the data presented in the literature. Several areas for improvement can thus be considered : - the optimization of prescription assistance software, through improvement of product sheets, use of protocols or optimization of alerts ; - the harmonization of pharmaceutical practices (writing and coding of interventions) ; - communication to prescribers and pharmacists, especially juniors, about most frequent pharmaceutical interventions.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-02988334
Contributor : Frédérique Gambade <>
Submitted on : Wednesday, November 4, 2020 - 4:47:58 PM
Last modification on : Saturday, November 14, 2020 - 3:10:59 AM

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Aude Tarré. Analyse rétrospective sur trois ans des Interventions Pharmaceutiques au Centre Hospitalier Universitaire de Toulouse. Sciences du Vivant [q-bio]. 2020. ⟨dumas-02988334⟩

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