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Master Thesis

Œil collyres et conservateurs. Le chlorure de benzalkonium : conséquences et alternatives de conservation des collyres à usage domestique

Abstract : The eye is a complex and priceless key organ of human body. It can face attacks thanks to combined protections giving by its well-organized anatomy but it’s submitted to a delicate balance which making it sensible too. Through the analysis of the composition of eye drops, and especially preservatives, one has come to light: benzalkonium chloride. This component, widely used in many other area than ophthalmology, has in one hand many interesting properties but, in the other hand, more and more studies demonstrate side effects, mainly for long term use, affecting equally surface and deep layers of the eye. Many people around the world are concerned by eye drop chronic use in treatment for allergies, dry eye or glaucoma. Some alternatives have been found such as using new preservatives systems or preservative free solutions allowed by innovating primary containers. Both strategies have benefits and weaknesses and must consider many factors like the time-consuming research, financial costs, patient compliance or environmental impact.
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Submitted on : Thursday, November 5, 2020 - 3:39:27 PM
Last modification on : Saturday, November 14, 2020 - 3:10:59 AM

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Marc Darie. Œil collyres et conservateurs. Le chlorure de benzalkonium : conséquences et alternatives de conservation des collyres à usage domestique. Sciences du Vivant [q-bio]. 2020. ⟨dumas-02990510⟩

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