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Master Thesis

Issues des grossesses obtenues en FIV pour endométriose : état de santé des mères et des enfants

Abstract : Introduction: Endometrios is is a chronic estrogen dependent disease that affects 10% of women of childbearing age. The main symptoms found are chronic pelvic pain, infertility, dyspareunia and dysmenorrhea. Traditionally, pregnancy is considered as beneficial to women with endomet riosis. However, some recent studies were concerned regarding the evolution of the pregnancy in women with endometriosis . It was especially notice some abnormalities of the localisation of the placenta, premature birth, small for gestational age, mis carriages, and cesarean birth. The aim of our study is to determinate whether the endometriosis has a bad effect on the pregnancies outcomes. Methods: We conducted a retrospective, non interventional and anonymous monocentric cohort study on pregnanci es obtained by IVF and ICSI in the AMP IMR Rocca center (Alphabio Bouchard) in Marseille between 2011 and 2017, as part of a study exposed / unexposed with endometriosis as an exposure factor. We studied maternal characteristics and the pregnancies outcome s to determinate if endometriosis has a bad effect on pregnancy. Results: Based on our results (n = 188), women with endometriosis are older than those treated for male infertility (p = 0.0076). Regarding obstetric characteristics, the rate of FCS and GEU is similar between our two populations (p = 0.5218) / (p = 0.0996). Only a medical termination of pregnancy is noted among our basic population. In terms of neonatal characteristics, women with endometriosis are less likely to give birth to children born prematurely (p = 0.5561). We find the same thing for children with a low weight for gestational age (p = 0.8305). No obstetric complications (Placenta previa, Preeclampsia and Postpartum hemorrhage) were found. Conclusion: Our study has allowed us to demon strate that endometriosis does not have a bad effect on the pregnancy outcomes. From now on, midwives working in a medically assisted procreation center will be able to transmit reassuring information and thus provide them with the best regarding the progr ess of their pregnancies.
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https://dumas.ccsd.cnrs.fr/dumas-03007776
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Submitted on : Monday, November 16, 2020 - 3:06:33 PM
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Camille Richaud. Issues des grossesses obtenues en FIV pour endométriose : état de santé des mères et des enfants. Gynécologie et obstétrique. 2020. ⟨dumas-03007776⟩

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