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Master Thesis

Grippe : quel impact sur la grossesse ?

Abstract : Introduction to the study: Influenza is a viral infection caused by a virus called Influenzae. The OMS estimates that it causes between 3 and 5 million serious cases, and 290 000 to 650 000 deaths per year worldwide. Pregnant women are like a population at risk. However, vaccination coverage is low. Objective: To describe the maternal-fetal and obstetrical prognosis of pregnant patients with seasonal flu. Methods: Literature review based on two databases: Pubmed Embase and Google Scholar. 16 articles were selected from 2011 to 2019. Results: Pregnant women have a higher risk of hospitalization compared to non-pregnant patients infected with influenza (OR 2.44 95% CI 1.22-4.87). The mortality rate is also 2.9 times higher (OR = 2.90 95% CI 0.48-17.72). Concerning newborns, fetal mortality is around 5.5% to 33% and the rate of prematurity is between 20% and 33%. Newborns are subject to an accumulated risk of birth defects (OR 2.00 95% CI 1.62– 2.48), and SGA (OR 1.24 95% CI 0.96–1.59 ). Exposure to the flu from early to mid-pregnancy is linked to a three times higher risk of schizophrenia in children. Conclusion: Vaccination therefore has a key role in preventing influenza in pregnant women. They have a higher risk of hospitalization, death and giving birth prematurely. In addition, their newborns are at risk of having SAG, developing birth defects, and schizophrenia in the future. It is therefore important that health professionals educate and inform patients.
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Submitted on : Wednesday, November 18, 2020 - 4:28:28 PM
Last modification on : Wednesday, October 27, 2021 - 8:41:36 AM
Long-term archiving on: : Friday, February 19, 2021 - 8:18:59 PM


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  • HAL Id : dumas-03012666, version 1


Laura Scorletti. Grippe : quel impact sur la grossesse ?. Gynécologie et obstétrique. 2020. ⟨dumas-03012666⟩



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