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Master Thesis

Excipients controversés dans l'industrie pharmaceutique et cosmétique : quelles alternatives possibles ?

Abstract : Over the last decade, people have been questioning the composition of medicines and cosmetic products before purchasing them. This interest increased with the arrival of new smartphone applications which can mark products and give information about their composition. A number of excipients are known to be controversial, i.e. are subject of a discussion which emerges from the population’s different opinions following the publication of scientific studies. The controversy may result from public concern about an excipient which could potentially be hazardous to human health. Such excipients include titanium dioxide and parabens. Titanium dioxide has many functions: colourant, opacifier, sun filter... It is now suspected of being a carcinogenic agent. Parabens are used as preservatives and are accused of being endocrine disruptors. The controversy over excipients can also be related to their environmental impact such as palm oil and silicones. Palm oil is used as an emollient, moisturizer or surfactant and has many derivatives. However, this substance is contentious as it is believed to be responsible for massive deforestation. Finally, silicones, used for their sensory qualities, are now being questioned as they appear to be non-biodegradable and would pollute the aquatic environment. Because of all these controversies and in order to meet the demands of the population, pharmaceutical and cosmetic industries are seeking for solutions to replace these contentious excipients and alternatives have now been found.
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Master Thesis
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Submitted on : Thursday, December 17, 2020 - 6:36:46 PM
Last modification on : Saturday, January 30, 2021 - 3:26:46 AM
Long-term archiving on: : Thursday, March 18, 2021 - 8:32:25 PM


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  • HAL Id : dumas-03080642, version 1


Léa Louvel. Excipients controversés dans l'industrie pharmaceutique et cosmétique : quelles alternatives possibles ?. Sciences pharmaceutiques. 2020. ⟨dumas-03080642⟩



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