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Master Thesis

Plainte cognitive et facteurs psychologiques associés chez les patientes après un cancer du sein

Abstract : Cognitive complaints are common adverse effects in cancer patients. Identifying subjects at risk could make it possible to limit their impact. We aimed to explore the relationship between current cognitive complaints and demographic and psychological factors in a group of breast cancer survivors. Through an online survey, cancer survivors reported current cognitive complaints using the FACT-Cog questionnaire (Perceived Cognitive Impairment) and answered questions about their demographic, lifestyle and cancerrelated characteristics. Anxiety, depression, fatigue and post-traumatic stress symptoms were also assessed. We used multivariable logistic regression models to explore the relationships between current cognitive complaints and social and psychological factors. Among the 1393 breast cancer survivors, 47.2% (n=657) had current cognitive complaints. Chemotherapy (OR=2.26, 95%CI=1.67-3.05), age (OR21-44 vs. >65 =0.14, 95%CI=0.07-0.27), sleep difficulties (ORnever vs. often=2.41, 95%CI=1.47-3.95), frequency of psychotropic treatments (ORnever vs. >1/week=1.70,95%CI=1.23-2.36), post-traumatic stress symptoms (OR=2.05, 95%CI=1.57-2.69) and employment status (ORfull-time or part-time vs. sick leave=1.64, 95%CI=1.08-2.49) were strongly associated with current cognitive complaints. In this large study, about half of breast cancer survivors reported cognitive complaints, particularly after chemotherapy. Some risk factors should be detected early to prevent persistent cognitive complaints after cancer: mainly sleep difficulties or post-traumatic stress symptoms.
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Submitted on : Thursday, April 1, 2021 - 6:23:42 PM
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  • HAL Id : dumas-03188283, version 1


Clémence Boscher. Plainte cognitive et facteurs psychologiques associés chez les patientes après un cancer du sein. Médecine humaine et pathologie. 2020. ⟨dumas-03188283⟩



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