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Master Thesis

Analyse épidémiologique des endocardites infectieuses sur matériel : étude rétrospective de 2008 à 2018 de 203 cas à l’hôpital Saint-Joseph

Abstract : Introduction: infectious endocarditis (IE) still has significant morbidity and mortality. The incidence of IE occurring on cardiac equipment (pacemaker (PM), implantable cardiac defibrillator (ICD), prosthetic valve) continues to increase. Material and methods: we conducted a retrospective study including all cases of IE on cardiac equipment supported at St. Joseph's Hospital from 2008 to 2018. This series of hardware IE was compared to non-hardware IE. Results: 203 patients were included in the study. The median age is 75.9 [32.1-96.8] years. The majority of IE occur on prosthesis (62.8%), then PM (26.8%), DAI (5.15%). The aortic valve is the most affected (51 cases, 52.6% including 7 TAVI). The predominant infectious portal of entry is digestive (17.5%). Patients with equipment have less IE on the mitral valve. Carriers of intracardiac material show more pulmonary emboli. Surgical management was performed in 43 (44.5%) patients. Hospital mortality is 14.4%. The most frequently isolated germs are Streptococcus sp. (25.8% of cases in patients with intracardiac material). Transthoracic echocardiography was positive in 48 cases (49.5%) and transesophageal echocardiography in 81.4% of cases in patients with equipment. Cardiac CT or PET-scanner help diagnosis in 67% and 84.2% of cases, respectively. Conclusion: IE on intracardiac material whose frequency continues to increase, do not have the same characteristics as it is on the localization, the type of complications, the panel of isolated germs and the methods necessary for the diagnosis.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03200042
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Submitted on : Thursday, May 6, 2021 - 4:06:10 PM
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Caroline Guerniou. Analyse épidémiologique des endocardites infectieuses sur matériel : étude rétrospective de 2008 à 2018 de 203 cas à l’hôpital Saint-Joseph. Médecine humaine et pathologie. 2019. ⟨dumas-03200042⟩

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