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Master Thesis

Cancers hématologiques traités par greffe de cellules souches hématopoïétiques et cellules CAR-T : impacts d'un programme d'activité physique adaptée pendant la phase de traitement

Abstract : Objective : the primary objective was to evaluate the feasibility of an adapted physical activity (APA) program in patients with hematological cancer treated with hematopoietic stem cell transplantation or CAR-T cells during the treatment phase. The secondary objectives were to evaluate the level of physical activity and to measure the benefits on muscle strength, fatigue and quality of life. Method : 11 patients were included in the study, 6 in the experimental group with APA and 5 in the control group. All patients were evaluated at initial T, post-transplant T and final T. Feasibility was assessed by the percentage of sessions performed. Quality of life was assessed by the QLQ-C30, fatigue by the MFI-20, muscle strength by the grip test and physical activity level by the IPAQ and the wearing of a connected watch. Results : the adherence rate to APA sessions was 64%. The feasibility of wearing a connected watch was not demonstrated, so physical activity level was not recorded. The results of the total level of fatigue and muscle strength did not show significant positive results. Only the overall quality of life in the experimental group showed significant positive results in final T. Conclusion : the results confirm the feasibility of an APA program in this type of patients treated by cell therapy in the clinical hematology department of Rennes
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03344089
Contributor : Ufr Aps Rennes 2 Connect in order to contact the contributor
Submitted on : Tuesday, September 14, 2021 - 3:35:59 PM
Last modification on : Monday, October 11, 2021 - 2:24:03 PM

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  • HAL Id : dumas-03344089, version 1
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Clara Le Roux. Cancers hématologiques traités par greffe de cellules souches hématopoïétiques et cellules CAR-T : impacts d'un programme d'activité physique adaptée pendant la phase de traitement. Cancer. 2021. ⟨dumas-03344089⟩

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