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Master Thesis

Facteurs de risque environnementaux précoces et trajectoires développementales d’irritabilité et du trouble du déficit de l’attention avec ou sans hyperactivité

Abstract : Introduction: irritability is frequently related with attention deficit hyperactivity disorder (ADHD). Their combination predicts more severe symptoms and greater impairment in children. Therefore, it seems important to study their developmental variations jointly and to highlight specific risk factors which can be modified through preventive public health campaigns. The aim of this study is to explore the association between early childhood environmental risk factors and irritability and ADHD developmental trajectories from a population-based cohort. Methods: data was collected from the Quebec Longitudinal Study of Child Development that followed 1588 children from 5 months to 12 years of age. Social factors, parenting behaviors and parental psychopathology were considered as potential risk factors. The child’s behavior was rated by its schoolteacher yearly between the age of 6 and 12 years old. Developmental trajectories of ADHD and irritability were estimated through multitrajectory modeling. Multinomial regression analyses were carried out to estimate association between risk factors and developmental trajectories. Results: four trajectories were estimated: one low ADHD/low irritability which was considered as physiological and three pathological trajectories (moderate irritability, high ADHD, and high irritability/high ADHD). Compared to the reference group, the combined profile was associated with male gender (adjusted Odds Ratio (aOR) = 7.01, 95% Confidence Interval (95%CI)[4.67-10.54]), non-intact families (aOR = 2.11, 95%CI [1.38-3.22]), coercive parenting (aOR=1.57, 95%CI [1.02-2.42]), consistent parenting (aOR = 0.83, 95%CI [0.72-0.95]), parental impact (aOR = 0.90, 95%CI [0.80-1.00]) and maternal history of antisocial behavior in adolescence (aOR = 1.44, 95%CI [1.05-1.96]). Conclusion: public health campaigns targeting parenting behaviors should be considered to prevent severe child psychopathology.
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https://dumas.ccsd.cnrs.fr/dumas-03388851
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Submitted on : Wednesday, October 20, 2021 - 4:31:49 PM
Last modification on : Wednesday, December 1, 2021 - 3:48:17 AM

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  • HAL Id : dumas-03388851, version 1

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Marie Herbein. Facteurs de risque environnementaux précoces et trajectoires développementales d’irritabilité et du trouble du déficit de l’attention avec ou sans hyperactivité. Sciences du Vivant [q-bio]. 2021. ⟨dumas-03388851⟩

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