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Master Thesis

Évaluation de la posologie des anticoagulants oraux directs dans la fibrillation atriale chez les patients de 75 ans et plus, à l’entrée de deux services de gériatrie de la métropole bordelaise

Abstract : Introduction: DOAC occupies an increasing place in the therapeutic arsenal of the general practitioner for AF. Prescribing rules have been established to limit the hemorragic risk. The aim of our study was to analyze the right prescription of DOAC in AF in elderly population with increased risk of side effects. Material and methods : observational and descriptive study based on data’s collection, conducted between January 1, 2019 and March 31, 2020, including patients aged 75 and over treated with DOAC for AF upon admission of two geriatrics hospital departments in Bordeaux metropolitan area. Results: 316 patients have been included in the study. Among them 27,8 % of patients were treated with an inappropriate dose, with underdosing (18,4%) more frequent than overdosing (9,5%). The secondary analyse highlights potential misuse factors mainly corresponding to the dose reduction criteria of the current recommendations. Conclusion : although increasingly used in AF, including in elderly population which has major risk of complications, DOAC are not always optimally prescribed. Faced with the progressive aging of the population, it seems essential for prescribing physicians to be up to date in their knowledge and aware of the need for regular dosage reassessment, especially for elderly population.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03594208
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Submitted on : Wednesday, March 2, 2022 - 2:53:41 PM
Last modification on : Friday, March 4, 2022 - 3:31:44 AM

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Élodie Petit. Évaluation de la posologie des anticoagulants oraux directs dans la fibrillation atriale chez les patients de 75 ans et plus, à l’entrée de deux services de gériatrie de la métropole bordelaise. Médecine humaine et pathologie. 2022. ⟨dumas-03594208⟩

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