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Master Thesis

Le traitement des douleurs myofasciales par injection intra musculaire de toxine botulique de type A dans les muscles masticateurs : revue systématique de la littérature

Abstract : Background: currently there is no consensus in the treatment of myofascial pain of the masticatory muscles in patients with bruxism. Sometimes, conventional multidisciplinary treatments are not enough, and some patients do not achieve satisfactory results in terms of pain reduction. In recent years, the use of botulinum toxin type A (BTX-A) has diversified thanks to its hypotonic effect, but its analgesic effect remains debated. Objective: this systematic review of the literature aims to demonstrate the efficacy of BTX-A in the treatment of myofascial pain (MFP) of the masticatory muscles in patients with bruxism. Method: a literature search was carried out on Pubmed, Scopus and Embase between 2000 and 2021, with particular attention to randomized clinical trials, prospective studies and retrospective studies. Studies related to the treatment of myofascial pain in masticatory muscles by injection of BTX-A are selected. The parameters evaluated are pain on VAS or questionnaires and occlusal force measured by EMG. The results of the studies will then be compared and synthesized. The hypothesis is that the pain decreases in correlation with the chewing force. Results: of the 134 articles searched, 15 articles are included, 5 are double-blind randomized clinical trials, 3 are randomized clinical trials, 1 is a prospective randomized observational study, 2 are prospective observational studies and 3 are retrospective comparative studies. These studies show that BTX-A injected into the masticatory muscles causes a decrease in myofascial pain, correlated with a decrease in muscle strength. BTX-A appears to be as effective as conventional treatments but does not require patient compliance. It could be indicated in patients refractory to conventional treatments. Limitations: most of the samples studied are small. Only one study offers follow-up for up to 1 year after injections of BTX-A. No study related to multiple sessions of injections in the same patients. Conclusion: injections of BTX-A into masticatory muscles are effective and relatively safe at low doses in reducing myofascial pain. The use of BTX-A appears to be justified in patients with pain refractory to conventional treatments Keywords: Botulinum Toxin, Bruxism, Myofascial Pain, Bite force.
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https://dumas.ccsd.cnrs.fr/dumas-03627156
Contributor : Odonto Ub - Connect in order to contact the contributor
Submitted on : Friday, April 1, 2022 - 9:56:46 AM
Last modification on : Tuesday, April 5, 2022 - 3:37:08 AM

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Kim Gervasoni. Le traitement des douleurs myofasciales par injection intra musculaire de toxine botulique de type A dans les muscles masticateurs : revue systématique de la littérature. Sciences du Vivant [q-bio]. 2022. ⟨dumas-03627156⟩

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