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Master Thesis

Apport de l’angiomammographie dans le bilan pré-thérapeutique du cancer du sein localisé

Abstract : Objective: A precise evaluation of the disease extent is mandatory before surgery for early breast cancer (EBC). Contrast-enhanced mammography (CEDM) is a recent technique that may help define adequate surgery. Methods: This retrospective study included consecutive patients referred to a cancer center between November 2016 and July 2017 for biopsy-confirmed invasive EBC management. The primary objective was to evaluate the rate of surgical changes after incorporating the results of the preoperative staging examination, including CEDM. Results: A total of 231 patients were screened for inclusion, and 132 patients were included, corresponding to 134 lesions. The first surgical plan was modified for 33 patients (25%), which represented 34 lesions. For 8 patients (6%), the surgery was cancelled in preference for neoadjuvant chemotherapy; for 16 patients (12.1%), the primary tumor procedure was enlarged; and for 23 patients (17.4%) the lymph node management was modified. Surgery was changed only due to the CEDM results for 24 patients (18.5%) and consisted of a more invasive procedure due to a more extended, multifocal or multicentric lesion than seen on the standard imaging. Anatomopathological surgery piece findings were well correlated with contrast-enhanced mammography results. Overall, there was no increase in the delay between the planned date of surgery and the effective surgical procedure (median 0 days). Conclusion: CEDM added to preoperative staging helped define better surgical management without increasing delay in the surgical procedure.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03631008
Contributor : Claire Leboeuf Connect in order to contact the contributor
Submitted on : Tuesday, April 5, 2022 - 1:25:47 PM
Last modification on : Tuesday, April 12, 2022 - 3:45:11 AM

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Fanny Montrognon. Apport de l’angiomammographie dans le bilan pré-thérapeutique du cancer du sein localisé. Médecine humaine et pathologie. 2022. ⟨dumas-03631008⟩

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