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Master Thesis

Stratégies de prévention des infections sur cathéter en néonatologie

Abstract : Introduction: Catheter- associated bloodstream infections (CA-BSI) are the most common nosocomial infections in neonatal intensive care units. A multifaceted intervention was gradually implemented: it included the implementation of a database, practice guidelines for the insertion and maintenance of central lines, a handwashing campaign, the promotion of breast-feeding and a collaboration with a hygiene unit. The aim of this study was to evaluate the impact of this strategy on the reduction of CA-BSI. Methods: Clinical data were collected prospectively. The study population included all neonates with peripherally inserted central catheters from January 1, 2008, to December 31, 2011. At the time of study, criteria for CA-BSI included a positive blood culture, clinical and/or biological signs and 5 days of antibiotics. Results: Overall 653 infants (mean gestational age 30 weeks, mean birth weight 1380 g) and 741 catheters were included in the study. Gestational age, birth weight and catheterization duration were similar on the four years. The incidence of CA-BSI decreased significantly between 2008 and 2011 (from 19,1 % to 6,2 % and from 13,8 to 4,4 per 1000 catheters days) . The mean annual decrease was of 4,8 % [95 % CI : 0-9,5%]. Conclusion: This study demonstrates that a multifaceted intervention can lead to the reduction of CA-BSI. Infection rates can be reduced by the application of strict protocols, the education of physicians and nurses and a close collaboration between all health workers.
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Master Thesis
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Submitted on : Tuesday, January 7, 2014 - 11:18:08 AM
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  • HAL Id : dumas-00924836, version 1


Johanna Parra. Stratégies de prévention des infections sur cathéter en néonatologie. Médecine humaine et pathologie. 2013. ⟨dumas-00924836⟩



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