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Master Thesis

La drépanocytose au Sénégal‎ : un exemple de médecine traditionnelle

Abstract : Sickle cell aneamia is a hereditary serious disease of haemoglobin leading to an alteration of the structure of the red globules which take the shape of sickle. It is widely spread in Africa and especially in Senegal. There is no curative treatment at the moment ant symptomatic treatments are very expensive. Most Senegalese can't afford "western" medicine and look for traditional medicine which is not regulated in Senegal. The botanic garden in Mbour cultivates herbs, makes herb-teas with Zanthoxylum zanthoxyloides (Rutaceae) and Cajanus cajan (Fabaceae) to prevent and treat crises due to sickle cell aneamia. These two plants have been studied in other countries and are commercialized as improved traditional drug. Their active principles (flavonoids, phenolic acids, amino acids) inhibit the transformation of red globules into sickles and have an effect on the inflammation and oxidization provoked by the disease. Both plants give promising results which have yet to be improved in order toachieve standardized drug forms.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-01070172
Contributor : Jean-Hugues Morneau <>
Submitted on : Tuesday, September 30, 2014 - 4:59:49 PM
Last modification on : Wednesday, July 15, 2020 - 8:56:03 AM
Long-term archiving on: : Wednesday, December 31, 2014 - 11:20:23 AM

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  • HAL Id : dumas-01070172, version 1

Citation

Céline Carboni. La drépanocytose au Sénégal‎ : un exemple de médecine traditionnelle. Sciences pharmaceutiques. 2009. ⟨dumas-01070172⟩

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