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Master Thesis

Prostatic artery embolization in 420 patients with lower urinary tract symptoms or chronic urinary retention: early outcomes and risk factors in a French multicentric retrospective study

Abstract : The aim of this a multicentric retrospective French study was to assess the safety, early clinical outcomes and the predictive factors of good clinical outcomes of the prostate artery embolization (PAE). Materials and methods: this first French multicentric retrospective study enrolled 420patients (mean age 69.7; mean IPSS 20.6) in 7 French university hospitals centers with bothersome LUTS and/or AUR due to BPH, refractory to medical treatment and managed by PAE from January 2017 to April 2019. Clinical outcomes (IPSS, QoL and subjective findings), imaging outcomes (prostate volume) and technical data (procedural and fluoroscopy times, uni/bilateral embolization, embolic agents, volume injected) using Redcap (a secure web platform). Univariate and multivariate were performed with logistic regression analysis adjusting for population characteristics to search for predictive factors. Results: technical success was 98.6% with a mean procedure time of 132,7 minutes. Clinical success was achieved in 269 patients among 320 patients with early clinical follow-up (84,1%) with a mean IPSS reduction of 53,6%, QoL reduction of 2,9 points and prostate volume reduction of 22,7%. 3 gland necrosis and 3 acute urinary retention were reported and no other major complication. Follow-up ranged from 1 to 31,2 months. Conclusion: this multicentric study strengthen the safety and feasibility of PAE with good early clinical outcomes, especially in young patients (<70 yo), with large prostate gland (>100ml) treated by bilateral embolization. Further long-term follow-up trials are required to consolidate these functional outcomes.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-02868586
Contributor : Scd Université de Montpellier <>
Submitted on : Monday, October 12, 2020 - 5:19:03 PM
Last modification on : Thursday, February 4, 2021 - 3:10:55 AM

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  • HAL Id : dumas-02868586, version 1

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Asmaa Belaouni. Prostatic artery embolization in 420 patients with lower urinary tract symptoms or chronic urinary retention: early outcomes and risk factors in a French multicentric retrospective study. Human health and pathology. 2019. ⟨dumas-02868586⟩

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