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Master Thesis

Évolution des caractéristiques périnatales des nouveau-nés ayant bénéficié d’un traitement par hypothermie contrôlée entre 2012 et 2018 en Basse-Normandie

Abstract : Neonatal hypoxic ischemic encephalopathy (HIE) is one of the most common causes of severe neurological deficit in children, affecting an estimated 2 per 1000 live births. Several reviews have suggested that therapeutic hypothermia reduces mortality and improves survival with normal neurological outcome and is now a standard treatment protocol for most neonatal centers. At Caen CHU, newborns with hypoxic ischemic encephalopathy can be treated by therapeutic hypothermia since 2011. The object of this study was to determine whether the patients treated by therapeutic hypothermia between 2012 and 2018 in your center were similar concerning their perinatals features. Eighty-four patients were included. We compared the pH at the cord, lactate at the cord and Apgar score at five life minutes. Secondary objectives, were to evaluate patients follow-ups and outcomes. In this study, the 84 treated patients by therapeutic hypothermia were not significantly different concerning their perinatals features. Concerning follow-up, 60% of treated patients were still followed at five years.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-02933308
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Submitted on : Tuesday, September 8, 2020 - 12:35:16 PM
Last modification on : Thursday, September 10, 2020 - 3:32:14 AM

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  • HAL Id : dumas-02933308, version 1

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Élise David. Évolution des caractéristiques périnatales des nouveau-nés ayant bénéficié d’un traitement par hypothermie contrôlée entre 2012 et 2018 en Basse-Normandie. Médecine humaine et pathologie. 2020. ⟨dumas-02933308⟩

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