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Master Thesis

Manifestations buccales inaugurales d'une maladie de Crohn chez l'enfant : 2 cas

Abstract : Introduction - Crohn's disease (CD) is a chronic inflammatory granulomatous disease whose orofacial manifestations are probably underestimated on clinical examination. There are very few published cases of the first oral manifestations of Crohn's disease in the pediatric population. The two reported cases present with Crohn's disease diagnosed through their unique oral symptomatology. Observation - Two 12 and 13 year old male patients were referred by oral cavity experts (pedodontist and maxillofacial surgeon) for specialist oral dermatology advice following the persistence of oral lesions for several years. These lesions included buccal mucosal hyperplasia (indurated tag-like lesions), cobblestone edema, granulomatous cheilitis, bilateral vestibular linear ulcerations, gingival enlargement, angular cheilitis, perioral erythema with areas of desquamation. Paraclinical examinations were carried out including a mucosal biopsy and a determination of fecal calprotectin. The results of these additional tests were in favor of Crohn's disease. The patients were referred to pediatric gastropediatrics where the diagnosis of Crohn's disease with colonic involvement was made and treatment implemented. Discussion - Few oral cavity practitioners are aware of the existence of inaugural oral symptoms of CD. These portend severe and extensive damage to the pathology. It is essential to know how to detect early CD from oral manifestations and to train specialists in the oral cavity. Early diagnosis should allow CD interception, and thus limit its progression while improving the quality of life of patients.
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Submitted on : Friday, March 5, 2021 - 9:45:54 AM
Last modification on : Friday, March 26, 2021 - 3:11:15 AM
Long-term archiving on: : Sunday, June 6, 2021 - 6:25:52 PM


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  • HAL Id : dumas-03160271, version 1




Catherine Nayl. Manifestations buccales inaugurales d'une maladie de Crohn chez l'enfant : 2 cas. Sciences du Vivant [q-bio]. 2020. ⟨dumas-03160271⟩



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