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Master Thesis

Comparaison de la tomosynthèse et de la mammographie synthétique versus la mammographie numérique dans la caractérisation et la visibilité des microcalcifications mammaires

Abstract : Purpose: To compare the performance of digital breast tomosynthesis (DBT) and synthetic mammography (SM) versus digital mammography (DM) and magnification views (MV), focusing on characterization and conspicuity of breast microcalcifications (MCA). Material and methods: We selected 81 patients that underwent breast macro-biopsy in our centre for a MCA cluster, between February 2018 and January 2020. Four breast radiologists with five to 31 years of experience in breast imaging and one resident radiologist read the 81 cases independently, ordered in three datasets, with substantial time interval in between to avoid any memory bias: DBT + SM views, DM, and MV. They recorded the size, number, morphology, distribution features, and conspicuity of the MCA cluster and also provided a BIRADS score from 3 to 5 for the suspicious MCA cluster. Results: All the readers found MCA more conspicuous on DM than on DBT + SM, with an odds ratio (OR) of 5.03 (p <0.001). The proportion of amorphous (= dust-like, cloud, cottony) MCA was greater on DM and MV versus DBT + SM (p < 0.001 and p = 0.001, respectively). DM depicted more MCA than DBT + SM (p <0.001). Detection of the MCA cluster was better on DM compared with DBT + SM (p <0.001). There was no significant difference between DM and DBT + SM for BI-RADS classification (p = 0.103). There was no significant inter-reader difference for conspicuity scores or detection of MCA clusters (p = 0.3 and 0.2 respectively). There were significant inter-reader differences concerning morphology features on DBT + SM (p <0.02) and on DM (p < 0.02), as well as distribution features and BI-RADS classification on each modality (p <0.003 and p <0.004 respectively). Conclusion: There are significant differences concerning characterization and conspicuity of MCA between DBT + SM and DM. Based on our results, small MCA and the amorphous MCA type are likely to be less conspicuous on DBT + SM.
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Master Thesis
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https://dumas.ccsd.cnrs.fr/dumas-03617730
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Submitted on : Wednesday, March 23, 2022 - 4:30:58 PM
Last modification on : Thursday, March 24, 2022 - 3:40:39 AM

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Hélène Coudert. Comparaison de la tomosynthèse et de la mammographie synthétique versus la mammographie numérique dans la caractérisation et la visibilité des microcalcifications mammaires. Médecine humaine et pathologie. 2021. ⟨dumas-03617730⟩

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