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Master Thesis

Radioembolisation hépatique avec les microsphères radiomarquées à l’Yttrium-90 : présentation générale et exemple de la pratique bordelaise

Abstract : Treating cancer directly at the tumor site while preserving healthy neighbouring tissues seems to be an ideal alternative for neoplasia treatment. Liver tumors show a high mortality rate and the existing therapies proposed have not achieved entirely satisfactory results. In nuclear medecine, selective or vectored internal radiotherapies treat cancer while preserving the healthy tissues. Among them, selective internal radiotherapy, also called radioembolization, with Yttrium-90-labelled microspheres is an innovative selective hepatic tumor protocol, selective of hepatic tumors. It is about introducing spheres with a diameter of a few tens of microns radiolabelled with a radionuclide directly into the liver to destroy the tumor in situ. The first results are encouraging and randomized clinical trials whose conclusions are expected for the next few years have been launched in order to collect robust data and optimize the place of this therapy in the hepatic neoplasias management.
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https://dumas.ccsd.cnrs.fr/dumas-01615902
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Submitted on : Thursday, October 12, 2017 - 6:19:53 PM
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Étienne Counilh. Radioembolisation hépatique avec les microsphères radiomarquées à l’Yttrium-90 : présentation générale et exemple de la pratique bordelaise . Sciences pharmaceutiques. 2017. ⟨dumas-01615902⟩

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